TitleImmunohistochemical evaluation of apoptosis and proliferation in the mucous membrane of selected uterine regions in pre-pubertal bitches exposed to low doses of zearalenone
Journal titlePolish Journal of Veterinary Sciences
Divisions of PASNauki Biologiczne i Rolnicze
PublisherPolish Academy of Sciences Committee of Veterinary Sciences ; University of Warmia and Mazury in Olsztyn
ReferencesVandenberg (2012), DR vom Saal Hormones and endocrine - disrupting chemicals : low - dose effects and nonmonotonic dose responses, Endocr Rev, 33. ; Freeman (2013), Prevalence and effect of uterine luminal reefluid on pregnancy and litter size in bitches, Theriogenology, 80, 73, doi.org/10.1016/j.theriogenology.2013.03.024 ; Zielonka (2015), Zearalenone in the intestinal tissues of immature gilts exposed per os to Mycotoxins, Toxins, 7, 3210, doi.org/10.3390/toxins7083210 ; Liu (2008), The genome landscape of ERα - and ERβ - binding DNA regions, Proc Natl Acad Sci USA, 105. ; McManus (1999), Frequency and severity of mastocytemia in dogs with and without mast cell tumors : cases, J Am Vet Med Assoc, 120, 1995. ; Hoffmann (1996), Reproductive endocrinology of bitches, Anim Reprod Sci, 42. ; De Bosschere (2002), Changes in sex hormone receptors during administration of progesterone to prevent estrus in the bitch, Theriogenology, 58. ; Frizzell (2011), Endocrine disrupting effects of zearalenone , alpha - and beta - zearalenol at the level of nuclear receptor binding and steroidogenesis, Toxicol Lett, 206. ; Silva (2012), Porcine reproductive and respiratory syndrome virus induces CD CD CD Foxp regulatory T cells, Virology, 8, 4. ; Frizzell (2015), Biotransformation of zearalenone and zearalenols to their major glucuronide metabolites reduces estrogenic activity, Toxicol In Vitro, 29. ; Tsumagari (2005), Induction of canine pyometra by inoculation of Escherichia coli into the uterus and its relationship to reproductive features, Anim Reprod Sci, 87. ; Stopa (2014), The effect of experimental exposure to low doses of zearalenone on uterine histology and morphometry in pre - pubertal bitche, Theriogenology, 82. ; Gajęcka (2015), The effect of low monotonic doses of zearalenone on selected reproductive tissues in pre - pubertal female dogs - a review, Molecules, 20, 20669, doi.org/10.3390/molecules201119726 ; Bryden (2012), Mycotoxin contamination of the feed supply chain : Implications for animal productivity and feed security, Anim Feed Sci Tech, 173. ; Zwierzchowski (2004), The occurrence of zearalenone and its derivatives in standard and therapeutic feeds for companion animals, Pol J Vet Sci, 7, 289. ; Calabrese (2005), Paradigm lost , paradigm found : the re - emergence of hormesis as a fundamental dose response model in the toxicological sciences, Environ Pollut, 138. ; Gajęcka (2012), The effect of low - dose experimental zearalenone intoxication on the immunoexpression of estrogen receptors in the ovaries of pre - pubertal bitches, Pol J Vet Sci, 15, 685. ; Waters (2014), Longevity in pet dogs : understanding what s missing, Vet J, 200. ; Galabova (2004), Steroid receptors in canine endometrial cells can be regulated by estrogen and progesterone under in vitro conditions, Theriogenology, 61, 963, doi.org/10.1016/j.theriogenology.2003.07.002 ; Grenier (2013), Modulation of intestinal functions following mycotoxin ingestion : meta - analysis of published experiments in animals, Toxins, 5, 396, doi.org/10.3390/toxins5020396 ; Gajęcka (2013), The effect of low doses of zearalenone and its metabolites on progesterone and β - estradiol concentrations in peripheral blood and body weights of pre - pubertal female Beagle dogs, Toxicon, 17, 76. ; Chu (2006), Degeneration and apoptosis of endometrial cells in the bitch, Theriogenology, 66. ; Bishop (2008), Non - genomic actions of progesterone and estrogens in regulating reproductive events in domestic animals, Vet J, 176. ; Cooke (2012), Uterine gland development begins postnatally and is accompanied by estrogen and progesterone receptor expression in the dog, Theriogenology, 78, 1787, doi.org/10.1016/j.theriogenology.2012.05.028 ; Brandon (2013), van de Ven Ten Does EU legislation allow the use of the Benchmark Dose ( BMD approach for risk assessment, Regul Toxicol Pharm, 67. ; Freeman (2013), Uterine artery blood flow characteristics assessed during oestrus and the early luteal phase of pregnant and non - pregnant bitches, Vet J, 197. ; Freeman (2013), Uterine fluid from bitches with mating - induced endometritis reduces the attachment of spermatozoa to the uterine epithelium, Vet J, 198. ; Gajęcka (2012), The low doses effect of experimental zearalenone ( ZEN ) intoxication on the presence of Ca in selected ovarian cells from pre - pubertal bitches, Pol J Vet Sci, 15, 2. ; Heberer (2007), Zero tolerances in food and animal feed - Are there any scientific alternatives ? A European point of view on an international controversy, Toxicol Lett, 175. ; Van Cruchten (2004), den haeseleer Proliferation patterns in the canine endometrium during the estrous cycle, Theriogenology, 62, 631, doi.org/10.1016/j.theriogenology.2003.11.015 ; Ververidis (2004), Serum estradiol - progesterone and respective uterine cytosol receptor concentrations in bitches with spontaneous pyometra, Theriogenology, 17, 614, doi.org/10.1016/j.theriogenology.2003.11.011 ; De Bosschere (2002), Estrogen - α and progesterone receptor expression in cystic endometrial hyperplasia and pyometra in the bitch, Anim Reprod Sci, 70. ; Greaves (2014), A guide to understanding the steroid pathway : New insights and diagnostic implications, Clin Biochem, 47. ; Barton (2012), Position paper : The membrane estrogen receptor GPER - Clues and questions, Steroids, 77. ; Boermans (2007), Mycotoxins and the pet food industry : toxicological evidence and risk assessment, Int J Food Microbiol, 119. ; Taylor (2010), Oestrogen receptor splice variants in the pathogenesis of disease, Cancer Lett, 288. ; Warner (2015), DHEA - a precursor of ERβ ligands, J Steroid Biochem, 145. ; Concannon (2011), Reproductive cycles of the domestic bitch, Anim Reprod Sci, 124. ; Böhm (2010), Survey and risk assessment of the mycotoxins deoxynivalenol zearalenone fumonisins and aflatoxins in commercial dry dog food, Mycotoxin Res, 26. ; Bondesson (2015), Estrogen receptor signaling during vertebrate development - Gene Regulatory Mechanisms, Biochimica et Biophysica Acta, 1849. ; Schlafer (2008), Cystic endometrial hyperplasia , pseudo - placentational endometrial hyperplasia , and other cystic conditions of the canine and feline uterus, Theriogenology, 70.