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Abstract

The prevalence of vitamin D deficiency in the American and European population is estimated to be extremely high. Although fewer people today suff er from serious health problems related to calcium and phosphate metabolism resulting from vitamin D deficiency, there are more and more studies suggesting that calcitriol may play an important role in the pathogenesis of other diseases in virtually every body system. A growing body of research shows that through its ubiquitously expressed receptor, calcitriol displays potent anti-angiogenic an anti-inflammatory activity. Th is review summarizes recent discoveries regarding these non-classical eff ects of vitamin D and their clinical implications. Data collection focused on the prevention and treatment of ocular diseases as well as on the underlying mechanisms.
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Abstract

Plastic obtained from the discarded computers, televisions, refrigerators, and other electronic devices is termed as e-plastic waste. E-plastic waste is non-biodegradable waste. This paper focuses to investigate the replacement of fine aggregate with plastic aggregate obtained from e-plastic. The paper presents a detailed comparison of concrete properties (i.e.: compressive strength, tensile strength, flexural strength, density and workability) for normal concrete and concrete containing e-plastic fine aggregates. The testing was conducted according to the ASTM standards. 28-day Compressive, Flexural and Split tensile strengths were determined. In addition to the effect of e-plastic fine aggregate, silica fume is added as an admixture to find the effect on strengths. Authors have performed a compressive, flexural and tensile test of concrete mix with various percentages of e-plastic aggregates (i.e., 0, 5, 10, 15 and 20%) and silica fume (i.e.: 0, 5 and 10%) and concrete densities are also considered. It has been concluded that an increase in the e-plastic fine aggregate results in reduction in densities, compressive, flexural and tensile strength values. However, when we add silica fume to the concrete mixture it leads to strength values similar to the control mixture. The optimum obtained concrete blend contained 5% e-plastic fine aggregates and 10% silica fume. The addition of silica fume in concrete mixtures increases the 28-day compressive, flexural and tensile strengths. Moreover, the density of concrete decreases with the increase in the e-plastic aggregates.
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Abstract

The aim of the study is to compare flexible pavement design lifespans and the main factors which create their values for a standard structure and one with an anti-fatigue course AF at different parameter values of pavement and its load, relevant to their design processes. Depending on the mixture used for the anti-fatigue course or the course thickness, durability improvement of the pavement (compared to the durability of a standard structure) can be obtained by extending the design lifespan of the asphalt base course or by extending the design lifespan of the AF course. On sections with predominantly slow traffic, the lifespan decreases significantly compared to sections with typical vehicle speed – the relative decrease is greater if anti-fatigue course is applied.
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