A new species of genus Panopea Menard de la Groye, named P. (P). andreae sp. n. is described in detail. It is the most common of bivalve species recorded in the Destruction Bay Formation (Early Miocene) of King George Island (South Shetland Islands, West Antarctica). The bivalve material collected includes in addition: P. (P) aff. worthingtoni Hutton, Eurhomalia cf. antarctica (Shermann and Newton) and E. cf. newtoni (Wilcknes).