At the current stage of diagnostics and therapy, it is necessary to perform a geometric evaluation of facial skull bone structures basing upon virtually reconstructed objects or replicated objects with reverse engineering. The objective hereof is an analysis of imaging precision for cranial bone structures basing upon spiral tomography and in relation to the reference model with the use of laser scanning. Evaluated was the precision of skull reconstruction in 3D printing, and it was compared with the real object, topography model and reference model. The performed investigations allowed identifying the CT imaging accuracy for cranial bone structures the development of and 3D models as well as replicating its shape in printed models. The execution of the project permits one to determine the uncertainty of components in the following procedures: CT imaging, development of numerical models and 3D printing of objects, which allows one to determine the complex uncertainty in medical applications.